trans-/de-differentiation
Patrick McNutt
pmmcnutt at princeton.edu
Tue Aug 6 12:51:05 EST 1996
In article <DvB8tx.3Fy at midway.uchicago.edu>,
aekentsi at woodlawn.uchicago.edu (alex emil kentsis) wrote:
> i am studying differentiation mechanisms and if you have references
> regarding trans- or de-differentiation, please post them. such studies
> would be very interesting.
> -alex.
>
> ZZ
Although I am pretty sure someone has already mentioned this to you, you
might want to look at newt limb regeneration- stump tissue
"dedifferentiate", become relatively homogenous fibroblast-like cells,
and then redifferentiate (often trans-differentiating) into adult cells
once more. J. Brockes is a great person to start with- you can use his
references to delve deeper. You also might want to look at Savard's book
on urodele limb regeneration.
I am studying regeneration, so if you have any problems/questions, feel
free to email.
Patrick McNutt
pmmcnutt at princeton.edu
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