Best cell line for keratinocyte differentiation?

Fergus Doherty mbxfd at
Wed May 15 10:22:29 EST 1996

Suggestions please for the best cell line to use to look at keratinocyte
differentiation.  I want a fairly easy to grow line (so no feeder cells,
collagen gels if possible) that will differentiate and goes as far as
possible in forming squames in reasonable numbers.

Are Hacats the best?


Fergus Doherty,
dept. Biochemistry,
University Medical School,
Queen's Medical Centre,
Nottingham NG7 2UH
Tel: (0)115 970 9366  FAX (0)115 942 2225 Internet:
Fergus.Doherty at

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