Are _forskolin_ and _U69593_ cAMP inhibitors?
engelhah at wright.aps.uoguelph.ca
Thu May 30 08:48:46 EST 1996
Bernard J. Hall (bjhall at neptune.ultranet.com) wrote:
> Hello there. Have been reading through some journal articles while researching
> a paper and have come across these two substances which seem to be cAMP
In the case of forskolin, it is the opposite: it activates adenylate
cyclase, thereby INCREASING intracellular cAMP. A useful reference:
Seamon et al., 1981 "Forskolin: Unique Diterpene Activator of
Adenylate Cyclase in Membranes and in Intact Cells" PNAS 78:3363.
I have never heard of the other one.
University of Guelph
hengel at aps.uoguelph.ca
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