How do I inhibit receptor internalisation ?

Alexander von der Lippe a.v.d.lippe at bio.uio.no
Fri Nov 8 05:18:40 EST 1996


In article <zakaria-2310962106580001 at isdn92.stud.uni-hannover.de>,
zakaria at ita.fhg.de (Hayssam Zakaria) wrote:

> I am looking for a method to keep a receptor on the cellsurface for a long
> period of time in the presence of its ligand. 
> Any idea how to get that accomplished ?? Maybe a chemical that inhibits
> the formation of clathrin coated vesicles ??
> 
>    Hayssam Zakaria

May be you could delete an internalisation motif in the cytoplasmic tail
of the receptor.

Alexander



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