How do I inhibit receptor internalisation ?
Alexander von der Lippe
a.v.d.lippe at bio.uio.no
Fri Nov 8 05:18:40 EST 1996
In article <zakaria-2310962106580001 at isdn92.stud.uni-hannover.de>,
zakaria at ita.fhg.de (Hayssam Zakaria) wrote:
> I am looking for a method to keep a receptor on the cellsurface for a long
> period of time in the presence of its ligand.
> Any idea how to get that accomplished ?? Maybe a chemical that inhibits
> the formation of clathrin coated vesicles ??
>
> Hayssam Zakaria
May be you could delete an internalisation motif in the cytoplasmic tail
of the receptor.
Alexander
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