How do I inhibit receptor internalisation ?

[Alexander von der Lippe]

In article <zakaria-2310962106580001 at isdn92.stud.uni-hannover.de>,
zakaria at ita.fhg.de (Hayssam Zakaria) wrote:

> I am looking for a method to keep a receptor on the cellsurface for a long
> period of time in the presence of its ligand. 
> Any idea how to get that accomplished ?? Maybe a chemical that inhibits
> the formation of clathrin coated vesicles ??
> 
>    Hayssam Zakaria

May be you could delete an internalisation motif in the cytoplasmic tail
of the receptor.

Alexander