hfeng at BLUE.WEEG.UIOWA.EDU
Tue Nov 12 11:36:12 EST 1996
As we know that the c-fms receptor's full size is 170kDa in feline sarcoma
virus, but we use different company's anti-c-fms mAbs or polyclonal
Abs that binding different size proteins in same tissue or cell line,
although these Abs only binded one band, but size is different, also same Ab
recognized different size's protein in different tissues or cell lines.
Is this problem using SDS-PAGE gels for more -s-s- domain protein? does
anybody can explain that is Abs problem( such as some Ab are not c-fms)
or homology is different? any suggestion or comment is highly appreciated.
Feng, H., DVM, Ph.D
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