p53 a nuclease?

JENNER R.G. RGJ20 at cam.ac.uk
Mon Oct 28 07:43:44 EST 1996

I'm a final year student studying Molecular Cell Biology at the University
of Cambridge, UK. This term we have to do a critical review of a paper in
the literature and I have chose 
"p53 Protein Exhibits 3'-to-5' Exonuclease Activity" by Mummenbrauer at
al. published in Cell 85 pp1089-1099 (June 28 1996)

Does anybody have any thoughts on the ideas and conclusions of the authors
or the validity of the experiments used? Any comments would be most


Richard Jenner  

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