Why Uracil?

Roger J. Young RYoung at lib.drury.edu
Wed Sep 25 09:48:36 EST 1996


With apologies if this is the incorrect newsgroup; but the question came up
yesterday as to why RNA uses Uracil rather than Thymine. One theory
suggested was that the presence of the extra "O" in ribose compared to
deoxyribose was compensated for by the loss of the "CH3" group in U
compared to T, based on some wild assumptions about steric hindrance etc.
Anybody actually know the real reason?

Many thanks

Roger Young





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