location of heterotrimeric G protein

[Cornelius Krasel]

pbpark (pbpark at NS.SUWON.AC.KR) wrote:
> Is there any references or evidences that the heterotrimeric G protein 
> can locate on the cellular organelles rather than the cell membrane?

Heterotrimeric G proteins have been found in the nucleus (look for
papers by Michael Crouch), endosomes, caveolae (that probably counts
as cell membranes) and other organelles. I am not aware of reports
localizing G proteins to mitochondria or the endoplasmatic reticulum
(except during synthesis :-).

--Cornelius.

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/* Cornelius Krasel, U Wuerzburg, Dept. of Pharmacology, Versbacher Str. 9 */
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