Are there Internal control genes, that are cell-cycle independent?

Martin Hartenstein Martin.Hartenstein at
Thu Dec 4 09:29:37 EST 1997

I'm investigating cell cycle progression by measuring changes in the
amount of cyclin mRNA by RT-PCR. For this I need an internal control gene
which is cell-cycle independent, since this is not so for commonly-used
internal references such GAPDH or b-actin. Are there any opinions about
suitable internal standard genes which are cell cycle independent?


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Martin.Hartenstein at

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