POSTDOCTORAL POSITION

Renny T. Franceschi rennyf at UMICH.EDU
Fri May 2 13:29:47 EST 1997


POSTDOCTORAL POSITION 
CELL AND MOLECULAR BIOLOGY OF 	BONE FORMATION

	*UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY

An NIH-funded position is available in July, 1997, to study mechanisms
of transcriptional regulation in osteoblasts. Studies are focused on the
identification and characterization of osteoblast-related promoter
elements and related transcription factors and their regulation by the
extracellular matrix and growth factors. Candidates must have a recent
Ph.D. and strong training in molecular biology with emphasis on
transcriptional regulation and/or extracellular matrix biochemistry.
Please contact:

Dr. Renny T. Franceschi
Associate Professor
Departments of Periodontics, Prevention and Geriatrics
and Biological Chemistry
University of Michigan School of Dentistry/Medicine
1011 No. University
Ann Arbor, MI 48109-1078
Telephone: 313 763-7381
email:rennyf at umich.edu 
					
References:

	Franceschi RT and Iyer BS, 1992, "Relationship between Collagen
Synthesis and Expression of the Osteoblast Phenotype.", J Bone Mineral
Res 7:235-246.

	Franceschi, R.T., Iyer, B.S., and Cui, Y. Effect of ascorbic acid on
collagen matrix formation and osteoblast differentiaiton in muringe
MC3T3-E1 cells. J. Bone Mineral Res.9:843-854, 1994.

	Xiao, G., Cui, Y-C, Ducy, P, Karsenty, G, and Franceschi, RT. Ascorbic
acid-dependent activation of the osteocalcin promoter in MC3T3-E1
preosteoblasts: Requirement for collagen matrix synthesis and an intact
OSE2 sequence. Molecular Endocrinology-In Press.

*The University of Michigan is an Equal Employment
Opportunity/Affirmative Action Employer and Specifically Invites Women
and Minorities to Apply.



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