breast cancer cell lines - positive control for apoptosis

Mike Miller mrm at WVNVM.WVNET.EDU
Tue Feb 24 16:50:30 EST 1998


The drug with which I work showed so far that it can induce increases in
3H-dT incorporation into DNA and in % S phase cells. Limitted studies
showed also increases in cell numbers. Is it possible that a drug can
induce increases in 3H-dT and %S phase cells but subsequently lead to
apoptosis? 
Does anyone know of a good positive control for apoptosis in breast
cancer cell lines (MCF7, T47D) ????? Please, HELP!!!



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