Ammonia and Immunological Response

Jay Mone' jmone at MARAUDER.MILLERSV.EDU
Tue Sep 8 08:42:18 EST 1998


I can't speak to the issue of non-specific suppression oif immune 
responses by ammonia, but I can say that ammonia could not induce a 
specific immune response.  There are two major resaons:
(1)  It's too small.  There are size and complexity requirements for 
immune recognition.  Its even too small to be hapten.
(2)  NH3 groups are extremely common in cells and extracellular 
fluids.  Immune responses against these molecular groups would be very 
bad for survival of the organism.

Jay Mone'



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