MOLECULAR BIOLOGY: ON RIBOSOMES

Rcjohnsen rcjohnsen at aol.com
Sun Oct 29 19:39:57 EST 2000


MOLECULAR BIOLOGY: ON RIBOSOMES
The dogma that nucleic acids are the repository of information
and that proteins catalyze chemical reactions was overturned only
15 years ago by the demonstration of catalytic RNAs (ribozymes).
Despite increasing support for the "RNA world hypothesis", which
sees RNA-based life forms as the progenitors of modern biological
cells, most biologists did not seriously consider the possibility
that RNA could be playing more than a minor part in reactions
such as protein synthesis. But it has turned out that in the
ribosome most of the important functional work is done by RNA,
and that the ribosome is "one colossal RNA enzyme".
(Nature 21 Sep 00 407:306) SCIENCE-WEEK http://scienceweek.com
27Oct00






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