Researchers Determine Structure of DNA Repair Prot

HHMI bionews at
Fri Aug 10 09:28:12 EST 2001

Research News from the Howard Hughes Medical Institute

Researchers Determine Structure of DNA Repair Protein

In every cell, a group of proteins called caretakers keeps vigil for signs
of DNA damage. If damage is encountered, the proteins act swiftly to repair
DNA and preserve the integrity of the genome. HHMI researchers have produced
the first images of a protein that detects and repairs broken strands of
DNA. The images show that the Ku protein is constructed to cradle DNA while
the DNA is repaired and rejoined with great precision.

Research published in the August 9, 2001, issue of the journal Nature.

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