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null p53 cells

Burhan Gharaibeh burhanco at yahoo.com
Thu May 23 10:24:26 EST 2002

Dear Colleagues,

I am working on a project that requires (as a control) human primary cells
that have no p53 or at least one null allele. I tried locating Li-Fraumeni
(+/- p53) fibroblasts to no avail. Literature has numerous rodent cell lines
with p53 -/- but I have not seen any for human.

Any ideas on where to find such cells? company name?
Any suggestions are greatly appreciated. 


Burhan Gharaibeh

Rangos Research Center
Children's Hospital of Pittsburgh
3460 Fifth Avenue
Pittsburgh, PA 15213
Tel. 412-692 6797


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