signal transduction

vivek tnvivek at
Wed Dec 31 07:47:09 EST 2003

I need some insights from the readers. I am interested in knowing the
differences in the function of related family of kinases like the Src
family members, they apparantly have similar substrate specificity and
SH2 and SH3 specificity and in certain cases similar tissue
expression.In such a scenario how do they signal differently(if at all
they do). individual KO's indicate differences in phenotypes. how
could this be acheived in cells?

thanks for the sugessions in advance.


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