[Cell-biology] Re: Questions on mitosis

[Eric]

henry at microtechnonstop.com wrote:
> 
> When it is time for a cell to divide (how does it know when?), part of
> the work involved is to duplicate its DNA (effectively, copying its
> nucleus first?). My question is regarding the sudden (?) hefty need for
> building blocks (deoxyribose, phosphate, purines and pyrimidines),
> where do they come from? How does the cell summon their timely
> presence? What is the "duplication rate," is it known how much time the
> cell needs to complete a second nucleus?
 
The daughter nuclei actually reform after the cell undergoes cytokinesis
though DNA is replicated and divided beforehand.

> Is this known to any degree at all? What websites would you recommend
> for details?

How about Molecular Biology of the Cell, Alberts et al.  A searchable copy
can be found at...
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowTOC&rid=mboc4.TOC&depth=2

See Chapter 17 and 18.
  17. The Cell Cycle and Programmed Cell Death
  18. The Mechanics of Cell Division

Eric