group I and group II introns

Scott A Hoffman schoffma at
Fri Nov 20 13:14:03 EST 1998

I am trying to categorize an intervening sequence as either a group I or
group II intron.  I'm not quite sure how to proceed.  Can anyone recommend
a good review article, book?  Are there any conserved sequences that I
should be looking for?  I understand that there is extreme sequence
diversity within these introns, would trying to fold the RNA into a 2°
structure to find conserved domains work?  If so what programs (mac based
or internet) for RNA folding should I be looking for?  Is there anything
else I should know?  Thanks in advance.


schoffma at

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