Steve Modena apparently had some difficulty in understanding
>In that last part there, what did he say? I've noticed that a certain
>biostatistician that I occasionally work with always talks in similar
>cryptobabble with me.
an earlier posting (whose name I don't recall)
>> The local alignment algorithm can locate matching segments within two
>>sequences. The non-intersecting alignment means the matchings in the
>>previous i local alignments will not be chosen as matching in the i+1 and
>>later local alignments if we want to find K local alignments.
>>
For anyone who has followed the sequence alignment literature this
should be fairly clear. A non-intersecting alignment is one that shares
no pair of aligned characters (i.e. a matching) with the other
alignment. In other words, alignment i shares no matching with the i+1
or later local alignments. Like most scientific specialties, the
sequence alignment field uses a technical vocabulary that it greatly
helps to learn. This does not make it cryptobabble. Abuse rarely leads
to understanding (my opinion).
Michael Gribskov
gribskov at ncifcrf.gov
--
Domain: curtiss at umiacs.umd.edu Phillip Curtiss
UUCP: uunet!mimsy!curtiss UMIACS - Univ. of Maryland
Phone: +1-301-405-6710 College Park, Md 20742
