[For those attending the AAAI conf this summer, note that
this conference is immediately preceding it.]
PRELIMINARY PROGRAM AND REGISTRATION MATERIALS
First International Conference on
Intelligent Systems for Molecular Biology
Washington, D.C.
July 6-9, 1993
Sponsored by:
The National Institutes of Health,
National Library of Medicine
The Department of Energy,
Office of Health and Environmental Research
The Biomatrix Society
The American Association for Artificial Intelligence (AAAI)
Poster Session and Tutorials:
Bethesda Ramada Hotel
Technical Sessions:
Lister Hill Center Auditorium, National Library of Medicine
For more information contact ISMB at nlm.nih.gov or FAX (608)262-9777
PURPOSE
This, the First International Conference on Intelligent Systems
for Molecular Biology, is the inaugural meeting in a series
intended to bring together scientists who are applying the
technologies of artificial intelligence, robotics, machine
learning, massively parallel computing, advanced data modelling,
and related methods to problems in molecular biology. The scope
extends to any computational or robotic system supporting a
biological task that is cognitively challenging, involves a
synthesis of information from multiple sources at multiple levels,
or in some other way exhibits the abstraction and emergent
properties of an "intelligent system."
FACILITIES
The conference will be held at
Lister Hill Center
National Library of Medicine
8600 Rockville Pike
NIH, Building 38A
Bethesda MD 20894
Seating in the conference center is strictly limited, so
registrations will be accepted on a first-come, first-serve basis.
Accomodations, as well as a reception and poster session, will be
at the
Bethesda Ramada Hotel
8400 Wisconsin Avenue
Bethesda MD 20814
A special room rate has been negotiated with the hotel, of $92/day
(expires 6/21). Attendees must make their own reservations, by
writing the hotel or calling (800)331-5252 and mentioning the
ISMB conference. To participate in a roommate matching service,
e-mail opitz at cs.wisc.edu.
TRANSPORTATION
The two facilities are within easy walking distance, convenient to
the subway (Metro Red Line, Medical Center stop), and from there
to the Amtrak station. Nearby airports include Dulles, National,
and Baltimore-Washington International.
PROCEEDINGS
Full-length papers from both talks and posters will be published in
archival proceedings. The citation is:
Proceedings of the First International
Conference on Intelligent Systems for
Molecular Biology (eds. L. Hunter,
D. Searls, and J. Shavlik) AAAI/MIT
Press, Menlo Park CA, 1993.
Copies will be distributed at the conference to registered
attendees, and will be available for purchase from the publisher
afterwards.
TALKS
Wednesday, July 7, 1993
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8:00-9:00am Continental Breakfast
9:00-9:15am Opening Remarks
9:15-10:30am Invited Talk
"Statistics, Protein Cores, and Predicted Structures"
Prof. Temple Smith (Boston University)
10:30-11:00am Break
11:00am "Constructive Induction and Protein Structure Prediction"
T.R. Ioerger, L. Rendell, & S. Surbramaniam
11:30am "Protein Secondary-Structure Modeling with Probabilistic
Networks" A.L. Delcher, S. Kasif, H.R. Goldberg, & W. Hsu
12:00-1:30pm Lunch
1:30pm "Protein Secondary Structure using Two-Level Case-Based
Reasoning" B. Leng, B.G. Buchanan, & H.B. Nicholas
2:00pm "Automatic Derivation of Substructures Yields Novel
Structural Building Blocks in Globular Proteins"
X. Zhang, J.S. Fetrow, W.A. Rennie, D.L. Waltz, & G. Berg
2:30pm "Using Dirichlet Mixture Priors to Derive Hidden Markov
Models for Protein Families" M. Brown, R. Hughey, A. Krogh,
I.S. Mian, K. Sjolander, & D. Haussler
3:00-3:30pm Break
3:30pm "Protein Classification using Neural Networks"
E.A. Ferran, B. Pflugfelder, & P. Ferrara
4:00pm "Neural Networks for Molecular Sequence Classification"
C. Wu, M. Berry, Y-S. Fung, & J. McLarty
4:30pm "Computationally Efficient Cluster Representation in
Molecular Sequence Megaclassification" D.J. States, N. Harris,
& L. Hunter
7:00-7:30pm Poster Setup
7:30-10:00pm Reception & Poster Session
Thursday, July 8, 1993
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8:00-9:00am Continental Breakfast
9:00-10:15am Invited Talk
"Large-Scale DNA Sequencing: A Tale of Mice and Men"
Prof. Leroy Hood (University of Washington)
10:15-10:45am Break
10:45am "Pattern Recognition for Automated DNA Sequencing:
I. On-Line Signal Conditioning and Feature Extraction for
Basecalling" J.B. Bolden III, D. Torgersen, & C. Tibbetts
11:15am "Genetic Algorithms for Sequence Assembly"
R. Parsons, S. Forrest, & C. Burks
11:45am "A Partial Digest Approach to Restriction Site Mapping"
S.S. Skiena & G. Sundaram
12:15-2:00pm Lunch
2:00pm "Integrating Order and Distance Relationships from
Heterogeneous Maps" M. Graves
2:30pm "Discovering Sequence Similarity by the Algorithmic
Significance Method" A. Milosavljevic
3:00pm "Identification of Human Gene Functional Regions Based on
Oligonucleotide Composition" V.V. Solovyev & C.B. Lawrence
3:30pm "Knowledge Discovery in GENBANK"
J.S. Aaronson, J. Haas, & G.C. Overton
4:00-4:30pm Break
4:30pm "An Expert System to Generate Machine Learning
Experiments: Learning with DNA Crystallography Data"
D. Cohen, C. Kulikowski, & H. Berman
5:00pm "Detection of Correlations in tRNA Sequences with
Structural Implications" T.M. Klingler & D. Brutlag
5:30pm "Probabilistic Structure Calculations: A Three-
Dimensional tRNA Structure from Sequence Correlation Data"
R.B. Altman
Friday, July 9, 1993
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8:00-9:00am Continental Breakfast
9:00-10:15am Invited Talk
"Artificial Intelligence and a Grand Unified Theory of
Biochemistry" Prof. Harold Morowitz (George Mason University)
10:15-10:45am Break
10:45am "Testing HIV Molecular Biology in in silico Physiologies"
H.B. Sieburg & C. Baray
11:15am "Identification of Localized and Distributed Bottlenecks
in Metabolic Pathways" M.L. Mavrovouniotis
11:45am "Fine-Grain Databases for Pattern Discovery in Gene
Regulation" S.M. Veretnik & B.R. Schatz
12:15-2:00pm Lunch
2:00pm "Representation for Discovery of Protein Motifs"
D. Conklin, S. Fortier, & J. Glasgow
2:30pm "Finding Relevant Biomolecular Features"
L. Hunter & T. Klein
3:00pm "Database Techniques for Biological Materials and
Methods" K. Baclawski, R. Futrelle, N. Fridman,
& M.J. Pescitelli
3:30pm "A Multi-Level Description Scheme of Protein
Conformation" K. Onizuka, K. Asai, M. Ishikawa, & S.T.C. Wong
4:00-4:30pm Break
4:30pm "Protein Topology Prediction through Parallel Constraint
Logic Programming" D.A. Clark, C.J. Rawlings, J. Shirazi,
A. Veron, & M. Reeve
5:30pm "A Constraint Reasoning System for Automating Sequence-
Specific Resonance Assignments in Multidimensional Protein
NMR Spectra" D. Zimmerman, C. Kulikowski, & G.T. Montelione
5:30-5:45pm Closing Remarks
POSTER SESSION
The following posters will be on display at the Bethesda Ramada
Hotel from 7:30-10:00pm, Wednesday, July 7.
[1] "The
