Methods to prove 2-sets of seq. are from diff. populations
excoffie at sc2a.unige.ch
Tue Jun 8 12:08:55 EST 1993
In article <1uududINNo3q at news.u.washington.edu>, joe at evolution.u.washington.edu (Joe Felsenstein) writes:
> In article <01GYK4XD2GG20003N8 at amc.uva.nl> kuiken at amc.uva.nl (Carla Kuiken) writes:
>>I'm trying to find a way to 'prove' that 2 sets of sequences are
>>from different populations. ...
>> ... They look different, and come out separate in phylogenetic
>>analysis, but bootstrapping doesn't give the distinction very high
> This would require someone to write a short program which would
> assign group memberships at random (by calling sequences "1" and "2"
> and then shuffling the array of 1's and 2's), and then computing the
> mean distances, and toting up a histogram of them.
> These kinds of permutation test are now very common in statistics.
> Joe Felsenstein, Dept. of Genetics, Univ. of Washington, Seattle, WA 98195
> Internet: joe at genetics.washington.edu (IP No. 22.214.171.124)
> Bitnet/EARN: felsenst at uwavm
This program already exists.
It is running under Windows 3.1 and is available by anonymous ftp on :
in the directory :
winamova.zip or amovazip.exe
Laurent Excoffier(*NT*) / Genetics and Biometry Lab / Dept. of Anthropology
U. of Geneva / 12, rue G. Revilliod / 1227 Carouge / Switzerland
Voice +41-22 702 6965 / Fax +41-22 300 0351 / Email: excoffie at sc2a.unige.ch
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