anyone looked at long-range patterns in DNA sequence?
xia at hardy.u.washington.edu
Tue Mar 23 18:15:22 EST 1993
In article <1993Mar17.153421.21757 at husc3.harvard.edu> mlevin at husc8.harvard.edu (Michael Levin) writes:
> Has anyone looked at long-range (much larger scale than average
>gene sizes) pattern in the genomes of various organisms? What I mean
>is, to take the entire (known) sequence of the genome of some
>organism, and treat it as a single long message in a 4-letter
>alphabet, ignoring the gene/promoter/etc. boundaries, to look for
>long-scale patterns. Has this been done or discussed anywhere? I would
>appreciate references. If such patterns were discovered, what would
>this imply? What tools (mathematical) can be used to look for patterns
>in a string of symbols (when the pattern isn't known in advance)?
>Please send ideas to mlevin at husc8.harvard.eddu.
You can use time series with different time (base) lags. What pattern
are you suspecting? It sounds pretty wild.
More information about the Comp-bio