IUBio

How to set window size of DNA

Keith Robison robison at lipid.harvard.edu
Thu Jun 15 21:12:36 EST 1995


Setting the window size is always a bugaboo.   There is 
a little bit of literature on it.  Try in SeqAnalRef, a
bibliography on sequence analysis maintained by Amos Bairoch,
available via http://expasy.hcuge.ch/

Some additional options include:
	1) Changing the windowing function.  Most programs
	   use a "square-wave" -- either something is in
	   the window or it isn't.  Various other functions
	   might be used which weight data at the outside
	   of the window less than data in the center.

	2) Computationally exorbitant, but possibly elegant,
	   is to look at _every_ window size.  I.e., draw
	   a 3D plot of value vs. position vs. window size.

Good luck!


Keith Robison
Harvard University
Department of Cellular and Developmental Biology
Department of Genetics / HHMI

robison at mito.harvard.edu 



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