Terence (bclong at uxmail.ust.hk) wrote:
> I often read in journals that a certain transmembrane topology is
> determined/predicted for a certain transmemnrane protein. How is this done?
> Is this done thru some commercial/public domain software? Or is it just by
> eyeballing how many hydrophobic segment there? Any hints will be welcomed.
Have a look at the following WWW page for one method you can use:
http://www.biochem.ucl.ac.uk/~jones/memsat.html
alternatively anonymous ftp to ftp.biochem.ucl.ac.uk and look in
pub/MEMSAT
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