Transcription Factor correlation with genes
Tania Broveak Hide
taniab at egenetics.com
Fri Jul 14 15:46:10 EST 2000
The STACK database, available from the South African National Bioinformatics
Institute, provides all human ESTs from GenBank clustered by general tissue
types. It is free for academics.
Stuart Brown <browns02 at med.nyu.edu> wrote in message
news:browns02-1307001348570001 at mcrcr1.med.nyu.edu...
> In article <87vgv6$ccl$1 at mercury.hgmp.mrc.ac.uk>,
> William.Nelson at karobio.se (William Nelson) wrote:
> > Transcription factors, for the most part, determine the
> > expression levels of genes in different tissues. I want to begin looking
> > at
> > some of the correlations between transcription factors and genes with
> > respect to different types of human tissue (heart vs. brain vs. kidney
> > etc.).
> > My idea is to look at ESTs generated from different tissues and identify
> > those ESTs that correspond to known genes. Then I want to search
> > PubMed or some other database and determine whether or not a particular
> > gene is associated with a particular transcription factor. I would like
> > to make this strategy as automatic as possible because I don't want to
> > burn out my eyes staring at the computer screen 24 hours a day.
> > Any suggestions are more than welcome.
> > file://William Nelson
> > Stockholm, Sweden
> Associated ESTs with tissues is essentially what has been done at the NCBI
> Genome Anatomy Project
> Perhaps that can be a starting point for you.
> Stuart M. Brown
> Bioinformatics Consultant
> NYU Medical Center, 550 First Ave, NY, NY
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