Transcription Factor correlation with genes

Tania Broveak Hide taniab at egenetics.com
Fri Jul 14 15:46:10 EST 2000


The STACK database, available from the South African National Bioinformatics
Institute, provides all human ESTs from GenBank clustered by general tissue
types.  It is free for academics.

See:  http://www.sanbi.ac.za

Stuart Brown <browns02 at med.nyu.edu> wrote in message
news:browns02-1307001348570001 at mcrcr1.med.nyu.edu...
> In article <87vgv6$ccl$1 at mercury.hgmp.mrc.ac.uk>,
> William.Nelson at karobio.se (William Nelson) wrote:
>
> > Transcription factors, for the most part, determine the
> > expression levels of genes in different tissues. I want to begin looking
> > at
> > some of the correlations between transcription factors and genes with
> > respect to different types of human tissue (heart vs. brain vs. kidney
> > etc.).
> > My idea is to look at ESTs generated from different tissues and identify
> > those ESTs that correspond to known genes. Then I want to search
> > PubMed or some other database and determine whether or not a particular
> > gene is associated with a particular transcription factor. I would like
> > to make this strategy as automatic as possible because I don't want to
> > burn out my eyes staring at the computer screen 24 hours a day.
> > Any suggestions are more than welcome.
> >
> > file://William Nelson
> > Stockholm, Sweden
>
> Associated ESTs with tissues is essentially what has been done at the NCBI
> Cancer
> Genome Anatomy Project
>
> http://www.ncbi.nlm.nih.gov/CGAP/hTGI/
>
> Perhaps that can be a starting point for you.
>
> --
> Stuart M. Brown
> Bioinformatics Consultant
> NYU Medical Center, 550 First Ave, NY, NY
>
>








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