The STACK database, available from the South African National Bioinformatics
Institute, provides all human ESTs from GenBank clustered by general tissue
types. It is free for academics.
See: http://www.sanbi.ac.za
Stuart Brown <browns02 at med.nyu.edu> wrote in message
news:browns02-1307001348570001 at mcrcr1.med.nyu.edu...
> In article <87vgv6$ccl$1 at mercury.hgmp.mrc.ac.uk>,
>William.Nelson at karobio.se (William Nelson) wrote:
>> > Transcription factors, for the most part, determine the
> > expression levels of genes in different tissues. I want to begin looking
> > at
> > some of the correlations between transcription factors and genes with
> > respect to different types of human tissue (heart vs. brain vs. kidney
> > etc.).
> > My idea is to look at ESTs generated from different tissues and identify
> > those ESTs that correspond to known genes. Then I want to search
> > PubMed or some other database and determine whether or not a particular
> > gene is associated with a particular transcription factor. I would like
> > to make this strategy as automatic as possible because I don't want to
> > burn out my eyes staring at the computer screen 24 hours a day.
> > Any suggestions are more than welcome.
> >
> > file://William Nelson
> > Stockholm, Sweden
>> Associated ESTs with tissues is essentially what has been done at the NCBI
> Cancer
> Genome Anatomy Project
>>http://www.ncbi.nlm.nih.gov/CGAP/hTGI/>> Perhaps that can be a starting point for you.
>> --
> Stuart M. Brown
> Bioinformatics Consultant
> NYU Medical Center, 550 First Ave, NY, NY
>>
