Salt bridges

[Mavrommatis Kostas]

Hi everybody,
does anybody knows if there is an experimental method for identifying the
formation of a salt bridge, apart from structural studies?
I have some mutants of a protein that are supposed to form different number
of salt bridges and I want to verify this.
Is there a way to do this by using chaotropic salts or DSC? or something
else?

I thank you in advance.