Cayte wrote:
>> In the following Kabat data, do the letter subscripts after 100, represent
> alternatives?
>> SEQTPA 109 100 gat ASP D
> SEQTPA 110 100A cta LEU L
> SEQTPA 111 100B ccg PRO P
> SEQTPA 112 100C cac HIS H
> SEQTPA 113 100D aat ASN N
> SEQTPA 114 100E gat ASP D
> SEQTPA 115 100F ggt GLY G
> SEQTPA 116 100G --- --- -
> SEQTPA 117 100H --- --- -
> SEQTPA 118 100I --- --- -
> SEQTPA 119 100J --- --- -
> SEQTPA 120 100K ttt PHE F
>> Thank you for any information.
>> Cayte
I don't think so. I have previously encountered this sort of numbering
with a protein
that was numbered with reference to another protein, and the 100A etc
appeared where
the protein had insertions as compared to the reference sequence. You
will probably
need to hunt down the paper introducing this sequence if you want to
know exactly which
protein is considered to be the reference.
best wishes,
Bent Nagstrup