Kabat

[Bent Nagstrup Johansen]

Cayte wrote:
> 
>   In the following Kabat data, do the letter subscripts after 100, represent
> alternatives?
> 
> SEQTPA        109   100 gat ASP D
> SEQTPA        110  100A cta LEU L
> SEQTPA        111  100B ccg PRO P
> SEQTPA        112  100C cac HIS H
> SEQTPA        113  100D aat ASN N
> SEQTPA        114  100E gat ASP D
> SEQTPA        115  100F ggt GLY G
> SEQTPA        116  100G --- --- -
> SEQTPA        117  100H --- --- -
> SEQTPA        118  100I --- --- -
> SEQTPA        119  100J --- --- -
> SEQTPA        120  100K ttt PHE F
> 
>   Thank you for any information.
> 
>                                       Cayte

I don't think so. I have previously encountered this sort of numbering
with a protein
that was numbered with reference to another protein, and the 100A etc
appeared where
the protein had insertions as compared to the reference sequence. You
will probably
need to hunt down the paper introducing this sequence if you want to
know exactly which
protein is considered to be the reference.

best wishes,
	Bent Nagstrup