IUBio

Computational prediction of microarray probe set behaviour

Mark Carroll markc at chiark.greenend.org.uk
Fri Oct 11 23:59:45 EST 2002


I was wondering how microarray probe set design software manages to
evaluate the alternative probes - with what algorithms one can
computationally predict a candidate probe's melting point, the extent
to which it will hybridise with a given target under particular
conditions, etc., and also if there are any public
experimentally-derived data sets against which one can test one's
prediction techniques. So far, I've failed to find any good overviews
of the state of the art.

Also, am I posting to the correct group, or would somewhere like
bionet.biophysics be better?

-- Mark




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