[Computational-biology] Biochemical Simulation post-doc position

dsamuels at vbi.vt.edu dsamuels at vbi.vt.edu
Fri Nov 18 13:40:07 EST 2005

Simulation of the Mitochondrial Toxicity of Nucleoside Analogs

The Virginia Bioinformatics Institute (VBI) invites applications for an
AIDS Therapy Modeler Postdoctoral Associate to work in the research group
of Dr. David C. Samuels on a project funded by NIH to study the
mitochondrial toxicity of AZT (zidovudine or Retrovir) and other
nucleoside analog drugs used in the treatment of HIV/AIDS.  The candidate
will be involved in computational modeling of the toxicity mechanisms of
these drugs, within a biomedical modeling research group and in
collaboration with a laboratory group that is carrying out experiments on
these drugs.  This position will involve further development of the
existing simulation, interaction with the lab-based collaborators and
supervision of one graduate student.  For an example of the simulation,
see our recent paper in Am. J Physiol. Cell Physiol., vol 288, pp
989-1002, 2005.

The successful candidate must have a PhD in a biological, mathematical or
computational field; experience in biochemical or cell biology modeling;
demonstrated creativity, independence, high motivation, and good
communication skills, demonstrated experience in developing publications
in peer reviewed high impact scientific journals based on individual
research; and possess strong work habits and the ability to work
independently as well as with research group.  Preferences will be given
to candidates having knowledge or experience with Mathematica, Systems
Biology Markup Language (SBML), or an equivalent modeling or simulation
system; or knowledge of mitochondrial biology or of antiviral therapy.

Duration of the appointment may be up to two years renewable annually
dependent on satisfactory performance and continuation of funding.  This
position will hold the special research faculty rank of Postdoctoral
Associate.  For more information on the university ranks for special
research faculty, please review the Special Research Faculty Handbook
located at http://www.provost.vt.edu/web_pages/faculty_handbooks.html.

Interested candidates should submit a letter of interest and CV upon
applying through www.jobs.vt.edu searching by posting number 042829. 
Successful candidates invited for interviews will be required to have
three letters of recommendation sent by the author directly to the
department as part of the application process.  Review of applications
will begin for this position on December 19, 2005.

Compensation is commensurate with experience.

The Virginia Bioinformatics Institute (VBI) at Virginia Tech has built an
internationally recognized scientific program with significant extramural
funding.  Areas of strength among the 16 research groups at VBI include
infectious diseases, ranging from the molecular to the population scale,
systems biology approaches to study stress response in several organisms,
modeling and simulation of biological networks, functional genomics,
metabolomics, proteomics and bioinformatics/computational biology. For a
closer look, visit us at www.vbi.vt.edu.

An Equal Opportunity/Affirmative Action Institution

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