The Center for Genomics and Bioinformatics (CGB Indiana University,
Bloomington) carries out research in genomics, bioinformatics and is a
principle laboratory of the Daphnia Genomics Project. This project creates
genomic resources for a developing model organism in ecological and
evolutionary genomics research. These resources include a 9-fold sequence
coverage of the genome that was produced by the U.S. Department of Energys
Joint Genome Institute in collaboration with the Daphnia Genomics
Consortium. As a result, Daphnia will soon have the best characterized
genome among Crustacea and will ultimately be used to address issues
relating to the genome structure of the arthropods.
The CGB has an immediate opening for a Research Fellow to help create and
implement algorithms that will rigorously test and help improve the
assembly of the genome sequence. The research fellow will also participate
in the exploration and interpretation of the data. This position is
initially funded for one year and is ideal for investigators who have
recently completed their graduate studies in the field of computer science
/ bioinformatics, or who are in the final stages of completing their
dissertations. However, all candidates with expertise in computer
programming and prior experience with genome sequencing projects are
encouraged to apply, including visiting scientists. We offer a competitive
salary ($57,000 plus benefits) and access to state of the art facilities.
Specifically, this project aims to improve the assembly of the Daphnia
genome by developing two computational methods for detecting misassembled
regions, one based on pattern statistics and another based on clone
coverage statistics. These independent algorithms are already proven to
accurately detect false assemblies in microbial genome sequencing
projects. These two algorithms will be refined and combined to provide a
probabilistic support index for scaffold junctions and will function on
much larger and more complex eukaryotic genomes, including Daphnia. A
significant outcome is the creation and implementation of a support index
along localized regions of genome sequence assemblies to indicate regions
of high and low confidence.
Applications will be accepted until October 31, 2005. Interested
candidates may contact John Colbourne for further information (by sending
email to jobs at cgb.indiana.edu). Please submit a CV and a description of
your background and interests, and have three (3) letters of
recommendation sent directly to the address below. Be sure to refer to
Research Fellow CGB-008 within your cover letter.
Attn: Research Fellow
Center for Genomics and Bioinformatics
1001 E. 3rd St.
Bloomington IN 47405-3700
Indiana University is an affirmative action equal opportunity employer.
Center for Genomics and Bioinformatics, Indiana University
915 East Third Street, Bloomington, Indiana USA 47405-7107
Daphnia Genomics Consortium - http://daphnia.cgb.indiana.edu/