Postdoctoral Position in Systems Biology - October 2006 (earliest)
Systems Biology of Apoptotic Cell Death Signaling Networks
Applications are invited for a Postdoctoral position in Systems Biology
(initially for three years) in the Department of Physiology and Medical
Physics/RCSI, Dublin, Ireland. The position is funded by the Health Research
Board Ireland (HRB).
Candidates should have a background in systems biology, computational
biology, biophysics or applied mathematics, and be experienced in numerical
analysis/programming (e.g. C++, MATLAB, Mathematica). Excellent written and
communication skills and a high level of motivation and commitment are
required. The institute is located in the heart of Dublin city and offers an
international and interdisciplinary working environment spanning the fields
of systems biology, cancer and molecular biology, biophysics, and
mathematics.
Apoptotic cell death is regulated by complex signalling networks spanning
several compartments within living cells. Impaired apoptosis can result in
developmental disorders and cancer. In an industry collaboration with
SIEMENS (Medical Division) the applicant will translate biological systems
into novel computational models that allow the spatiotemporal and
quantitative prediction of signalling events, and the identification of key
regulatory factors or threshold mechanisms deciding on apoptotic cell death.
The applicant will work interactively with the experimentalists to discuss
model validity and restrictions. Generated models will qualitatively and
quantitatively be validated by experimentalists measuring the real time
kinetics of key signalling events within living cells.
Applications should include CV and names and addresses of two referees and
be sent (preferably by e-mail) to:
Dr. rer. nat. Markus Rehm
Lecturer in Physiology and Biophysics
Department of Physiology and Medical Physics
Royal College of Surgeons in Ireland
York Street Building
Dublin 2
Ireland
email: mrehm at rcsi.ie
Key publications are available on request
