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[Computational-biology] Post-doc in Bioinformatics at the Samuel Roberts Noble Foundation

PatrickZhao via comp-bio%40net.bio.net (by patrick.zhao from gmail.com)
Fri Oct 13 15:43:54 EST 2006

We seek a post-doctoral fellow (Position #PB-S095-306, URL:
http://www.noble.org/Jobs/Employment.asp) to work on the bioinformatics
aspect of a project entitled Comparative genomics of secretory
trichomes - Biofactories for production of plant secondary
metabolites. The project is founded by National Science Foundation with
an award (#DBI-0605033) amount of approximately 1.4 million US dollars
over a period of 09/01/2006 - 08/31/2009. This multi-disciplinary
project combines genomics, informatics and molecular biology with
analytical biochemistry, enzymology, and metabolic engineering.

Research will be conducted in the laboratory of Dr. Patrick Xuechun
Zhao in the Plant Biology Division at the Noble Foundation. He/she will
be responsible for constructing a publicly available database of genes
and metabolites expressed in plant trichomes. The database will host
experimental information on trichome metabolite profiles, metabolic
pathways occurring in trichomes, and phenotypic consequences of gene
knock-out or silencing . Besides the required responsibility in
database development, curation, management and maintenance, he/she will
assist in problem identification and recommend enhancements to
analytical, processing, and statistical software.

He/she will also carry out independent research on various problems
raised by the project. Suggested research topics include, but are not
limited to:

* Algorithms on high-throughput gene and metabolite expressions
analysis and their applications for in planta expression analysis and
mining of trichome-expressed genes and metabolites.

* Data integration and data mining of heterogeneous plant genomics
data, including protein/ RNA/ DNA sequences, microarray gene
expressions, metabolites x-MS profiles, and phenotypes due to gene
manipulation, etc.

* Computational biology models of biological pathways and network


Preferred qualifications include: Education to the level of PhD in
bioinformatics / computational biology / computer science and/or
genomics and molecular genetics; Good understanding of plant genomics
and genetics research; Excellent oral and written communication skills;
Programming skills with at least one of the following languages: C/C++,
Perl, PHP and Java; Capability of developing bioinformatics
applications to aid basic research in plant science; Knowledge of SQL
language and SQL Server; Experience in developing large scale
scientific databases and data analysis systems. Experience in
bioinformatics, particularly in protein/ RNA/ DNA sequence analysis and
bioinformatics software, is desired.

The Noble Foundation is a private, non-profit organization focused on
the improvement of agriculture with state-of-the-art research,
greenhouse, laboratory, and office facilities. The Foundation offers
competitive salaries commensurate with experience and excellent
benefits. Applicants should send a CV, cover letter, and names and
addresses of three references to The Noble Foundation, Attn: Human
Resources, P.O. Box 2180, Ardmore, OK 73402 or you may email your CV
and application to NFHR from noble.org. Applications are available on-line
via the internet at www.noble.org or by calling toll free (866)

Patrick Xuechun Zhao, Ph.D.

Assistant Professor

Plant Biology Division
The Samuel Roberts Noble Foundation, Inc.
2510 Sam Noble Parkway
Ardmore, OK 73402 USA

mail: pzhao from noble.org

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