The National Institute for Mathematical and Biological Synthesis
(NIMBioS) is now accepting applications for its Investigative Workshop,
"Many-cell System Modeling <http://nimbios.org/workshops/WS_manycell>,"
<http://nimbios.org/workshops/WS_manycell> to be held July 7-9, 2015, at
NIMBioS.
*Objectives: *Biologists understand many rules governing single cell
behavior. Knowledge about cell-cell and cell-environment interactions is
rapidly accumulating. Given clearly stated rules and empirical data,
mathematicians formulate models for living systems expressed as
equations. Computational scientists then perform simulations solving
these equations to predict collective behavior over time. When billions
of cells must be simulated to reproduce emergent behaviors,
computational challenges can become overwhelming. Questions then arise:
When is cell-scale precision required to explain or predict collective
phenomena? What approximate (continuous) methods can be applied instead,
and when do they fall short? What methods exist to conduct many-cell
simulations directly? Computational scientists can adapt both continuum
and discrete agent-based simulation codes to high performance computing
(HPC) environments. Careful adaptation has the potential to bridge the
gap between one and one-billion cells, but corresponding models must
also be developed. This workshop will bring together modelers, computer
scientists and scientific computing experts to discuss state of the art
modeling and simulation of many-cell living systems. Some practitioners
use ad hoc methods to build and simulate models using general frameworks
such as MATLAB, FLAME, and C++. Others use paradigm-specific platforms
such as CompuCell, Morpheus, and Biocellion. Participants will learn
from shared experiences, match methodologies to modeling problems, and
match skills to modeling challenges. Workshop results and the new
relationships formed will serve as a foundation for future work in
addressing the challenges of moving from small-scale multicellular
models to modeling whole organisms and communities.
*Location: *NIMBioS at the University of Tennessee, Knoxville
*Co-Organizers: *Simon Kahan
<https://www.systemsbiology.org/simon-kahan> (Computer Science and
Engineering, Univ. of Washington; Northwest Inst. for Advanced
Computing); Nick Flann <http://digital.cs.usu.edu/%7Eflann/> (Computer
Science, Utah State Univ., Logan); Andrea Hawkins-Daarud
<http://labs.feinberg.northwestern.edu/swanson/about/people/index.html>
(Swanson Lab, Feinberg School of Medicine, Northwestern Univ.); Russell
Rockne <http://mathematicalneurooncology.org/?page_id=328> (Neurological
Surgery, Swanson Lab, Feinberg School of Medicine, Northwestern Univ.);
and Ryan Tasseff <https://www.systemsbiology.org/ryan-tasseff>
(Institute for Systems Biology, Seattle, WA)
For more information about the workshop and a link to the online
application form, go to http://nimbios.org/workshops/WS_manycell
Participation in the workshop is by application only. Individuals with a
strong interest in the topic are encouraged to apply, and successful
applicants will be notified within two weeks of the application
deadline. If needed, financial support for travel, meals, and lodging is
available for workshop attendees.
*Application deadline:* March 22, 2015
The National Institute for Mathematical and Biological Synthesis
(NIMBioS) (http://www.nimbios.org) brings together researchers from
around the world to collaborate across disciplinary boundaries to
investigate solutions to basic and applied problems in the life
sciences. NIMBioS is sponsored by the National Science Foundation, with
additional support from The University of Tennessee, Knoxville.
#
*****************************
Catherine Crawley, Ph.D.
Communications Manager
National Institute for Mathematical and Biological Synthesis (NIMBioS)
University of Tennessee
1122 Volunteer Blvd, Ste. 106
Knoxville, TN 37996
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