Self-Sustained Sequence replication

Kevin O'Donnell odonnell at
Fri Apr 28 05:51:13 EST 1995

Is anybody using SSSR* for anything? How does it compare to PCR/LCR 
in terms of sensitivity , specificity and ease of use?  also, can anyone 
explain the difference between SSSR (non-patented) and the to my eyes 
very similar NASBA (nucleic acid sequence based amplification) which is 

*self-sustained sequence replication entails amplification by RNA 
transcription, for anyone who's wondering what I'm on about.

Kevin O'Donnell
Scottish Agricultural Science Agency    

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