Self-Sustained Sequence replication

Garth Ehrlich ehr at MED.PITT.EDU
Fri Apr 28 09:25:34 EST 1995

<start of forwarded message>

3SR and NASBA are essentially identical.  Both were based upon 
Tom Gingeras's original RNA amplification system TAS (transcript
amplification system).  Tom then went on to develop 3SR, but in an
ironic twist of fate got beaten to the patent by Organon Teknika 
which independently developed NASBA from his TAS system.  If 
your interested in the original description of TAS it was published in 
Science in 1986.  You're welcome ot send this out to the net if you so 


Garth D, Ehrlich, Ph.D>
Director, Core PCR Facility
University of Pittsburgh

<end of forwarded message>

Dr Kevin O'Donnell		     
Diagnostics and Molecular Biology
Scottish Agricultural Science Agency    
Edinburgh                         		odonnell at          

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