Non-invasive diagnostics

Jesse Patton jcpatton at u.washington.edu
Fri May 24 14:34:13 EST 1996

Thanks for the reply.  I will try to address your three points below:

On Wed, 22 May 1996, Bert Gold wrote:

> On Wed, 22 May 1996, Jesse Patton wrote:
> This is a nice idea (below) but:
> 1) I'm not certain how this is non-invasive.

	It is non-invasive because the oxygen sensor is attached to the
skin of the patient, usually premature babies in incubators, and sealed
from the ambient air environment.

 > 2) Currently such blood gas analysis is carried out in
>    most places by looking at Arterial levels, how is what
>    you propose different?

	These sensors actually do measure arterial p02 levels.  Enough O2
permeates from the arterial vessels to the surface of the skin to allow
for accurate measurement with the very sensitive polarographic sensors.
Commercial products  have been on the market for at least 20 years.  Much
of the Premie measurements have been replaced with oximetry, which of
course does not measure arterial p02 but can infer it based on the
assumption that the heart/lung functions are normal - not always a safe

 > 3) I feel pretty convinced a separate newsgroup to explore
> biomedical engineering applications to diagnosis would
> be counter-productive.

	I was not suggesting that a separate newsgroup should be started.
I was attempting to follow your suggestion that this topic could become
part of this group.  I simply began with one example of non-invasive blood
gas detection.

Jesse C. Patton

 > Bert Gold > San Francisco
> > I would be interested in getting some dialouge going regarding
> > Transcutaneous Polarogrphic Oxygen and CO2 Sensors.  Several years back I
> > worked to develop a silicon-based Clark type sensor that utilized
> > structurally firm (cross-linked) hydrophilic membranes as electrolye media
> > for these sensors.  These "flat-beaker" membranes fit nicely with planar
> > designs and processes for silicon chip sensors.  Any interest?

More information about the Diagnost mailing list

Send comments to us at biosci-help [At] net.bio.net