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Antibody interactions

daemon at hgmp.mrc.ac.uk daemon at hgmp.mrc.ac.uk
Thu Feb 17 04:10:42 EST 2000




-----Original Message-----
From: Robert Burns [mailto:burns at sasa.gov.uk] 
Sent: 16 February 2000 11:36
To: diagnost at net.bio.net
Subject: Antibody interactions


We have come across a curious phenomenon when making cocktails of
monoclonals. Two of our mab/Alk.phos conjugates which detect Potato
Virus A
pick up an isolate of this virus individually in ELISA. However when a
mixture of the two conjugates is used we cannot detect this isolate. Any
ideas of what is going on?


Robert Burns



Antibody Unit
SASA
Craigs Road
Edinburgh
EH12 8NJ

burns at sasa.gov.uk


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