Geotaxis Gene.

FlyBase Project Members flybase at MORGAN.HARVARD.EDU
Mon Aug 22 11:17:21 EST 1994


Dear Larry,

     I have attached a document containing reports on three genes
in FlyBase that mention geotaxis.  I obtained this by using
a gopher+ client to ftp.bio.indiana.edu, and doing a FlyBase
genes search for the word "geotaxis".

     These reports mention several citations that you might find
of interest.  You can get more complete information about each
citation by doing a reference search on the FlyBase gopher for
the FlyBase reference number given (e.g., FBrf0044446).

     Please send email to flybase at morgan.harvard.edu if you have
any questions or would like additional information about using
FlyBase services.

				Wayne Rindone for
				flybase at morgan.harvard.edu

0(1)  l(1)adl3  lethal-(1)-adl3  genemap: 1-
#
Gene symbol              : l(1)adl3
Not updated after        : 16 May 94      
Full name                : lethal-(1)-adl3
FlyBase gene id number   : FBgn0005414
Genetic map position     : 1- [y-cv]
Phenotypic information   :
   One of a series of EMS-induced
   mutants identified by virtue of their reduced life
   span upon being shifted from their developmental
   temperature of 22[o]C to 29[o]C shortly after
   eclosion.
Allele                      : l(1)adl3[1] 
   FlyBase allele id number : FBal0007401 
   Origin/mutagen           : ethyl methanesulfonate 
   Other misc. allele data  :
      Severely debilitated in phototaxis and geotaxis
      shortly after shift of adults raised at 22[o]C to 29[o]C 
      (Leffelaar and Grigliatti, 1984). 
      temperature-sensitive L2/L3 larval lethal
      temperature-sensitive female sterile
      adults die 6-8 days after eclosion at 29[o]C.
Gene Reference(s) :
   FBrf0044446 == Homyk et al., 1986, Genetics 113: 367--389 
   FBrf0040743 == Leffelaar and Grigliatti, 1984, Dev. Genet. 4: 211--227 
   FBrf0066905 == Lindsley and Zimm, 1992

------------------------------------- 

0(2)  l(1)ts66  lethal-(1)-ts66  genemap: rt.
#
Gene symbol              : l(1)ts66
Not updated after        : 16 May 94      
Full name                : lethal-(1)-ts66
FlyBase gene id number   : FBgn0005463
Genetic map position     : rt. of f
Allele                      : l(1)ts66[1] 
   FlyBase allele id number : FBal0007872 
   Origin/mutagen           : ethyl methanesulfonate 
   Other misc. allele data  :
      temperature-sensitive lethal
      Selected as a temperature-sensitive lethal in the
      presence of theophylline; hypersensitive to
      theophylline at 29[o]C, but not at 25[o]C. Mutant
      males contain lower levels of cyclic nucleotide
      phosphodiesterase than wild type and normal levels of
      adenyl cyclase. Exhibit increased motor activity at 29[o]C; 
      movements uncoordinated; flight and both 
      phototaxis and geotaxis impaired. Unable to learn
      (Savvateeva and Kamyshev, 1981; Savvateeva, Peresleny, Ivanushina
      and Korochkin, 1985).
Gene Reference(s) :
   FBrf0066905 == Lindsley and Zimm, 1992
   FBrf0037233 == Savvateeva and Kamyshev, 1981, Pharmacol. Biochem. Behav. 
      514: 603--611 
   FBrf0042389 == Savvateeva et al., 1985, Dev. Genet. 5(3): 157--172 

------------------------------------- 

0(3)  Shu  Shudderer  genemap: 1-55.1.
#
Gene symbol              : Shu
Not updated after        : 16 May 94      
Full name                : Shudderer
FlyBase gene id number   : FBgn0003402
Genetic map position     : 1-55.1.
Discoverer(s)            : R.L. Williamson.
Allele                      : Shu[1] 
   FlyBase allele id number : FBal0015642 
   Origin/mutagen           : ethyl methanesulfonate 
   Other misc. allele data  :
      Sudden leg jerks are frequent and enough to topple the
      fly; negative geotaxis is sluggish and seemingly not a
      consequence of shuddering bouts during climbing toward
      top of glass vials; neither of these behavioral
      abnormalities is pronounced in young adults, but they
      become maximal after about a week of adult life;
      lithium or ammonium ions placed in medium on which the
      mutant is grown reduce the severities of the eventual
      adult phenotypes. Homozygous females are not observed.
Gene Reference(s) :
   Hall, 1992, Lindsley and Zimm, 1992
   FBrf0023153 == Suzuki et al., 1971, Proc. natn. Acad. Sci. USA. 68: 
      890--893 
   FBrf0038676 == Williamson, 1982, Psychopharmacology 76: 265--268 

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