drosophila telomeres and recombination

[Jim Mason]

Meiotic recombination per unit length of chromosome is generally 
increased in distal regions. This, however, has been attributed to a 
"centromere effect", not an effect of telomeres (Beadle, PNAS 
18:160-165, 1932; Mather, Genetics 24:413-435, 1939). Further, most 
recombination-defective meiotic mutants have stronger effects distally, 
so that the distribution of exchanges is more nearly random along a 
chromosome arm (reviewed by Baker et al., Ann Rev Genet 10: 53-134, 
1976; Baker & Hall, The Genetics and Biology of Drosophila 1a: 351-434, 
1976). On the other hand, there is a very localized decrease in 
recombination next to the centromere. Recent work in this area has been 
by Chuck Langley, UC Davis, and Chip Aquadro, Cornell.jjc4 at po.CWRU.Edu 
(James J. Campanella) wrote:
>
>Dear Drosophila researchers,
>
>I have a quick question. Do drosophila have
>increased levels of recombination for
>markers near telomeres as in other higher
>organisms? I have searched the literature
>for an answer to that question without much
>luck.If you've got a reference,that would be
>even better. Thanks a lot.
>
>Jim Campanella
>Biolgy Dept.
>Case Western Reserve University
>Cleveland, Ohio 44106
>-- 
>"Sometimes the Road less travelled is less travelled for a
>reason."   - Jerry Seinfeld