antisense transformants?

Chris Jones jonesc at
Sat Oct 28 16:46:01 EST 1995

In article <46lm98$bn5 at>, Jens Riese
<jr2 at> wrote:

>Has anybody tried making antisense expressing transformants? I am 
>thinking of interfering with the function of a gene for which there are 
>no mutants, and this is a possibility I am considering. I would 
>appreciate hearing about any kind of experiences, positive or negative,
>to evaluate the feasibility of this approach.

The only paper I'm aware of is Qian et al., PNAS 85:9601-9605 (1988) --
have you tried searching FlyBase?

Chris Jones (jonesc at

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