Major FlyBase Update

FlyBase Project Members flybase at MORGAN.HARVARD.EDU
Wed Mar 27 13:06:59 EST 1996


Release 9603

FlyBase announces a major new release of the Drosophila database.

The genes file is an updated file with the addition of new genes and
alleles.  The total number of 'genes' in this release is nearly 10,000;
that of alleles is over 30,000. The number of aberrations is over 12,500.
The bibliography includes over 76,000 records, of which over 4000 are
theses.

The following are the more important structural changes:

1. The cross links to genes of other species (e.g. mouse, human, yeast)
that are reported to be 'similar' to Drosophila genes have been
extensively updated and now include gene symbols (and, where available,
unique identifier numbers) from the mouse (MGD), human (OMIM and GDB), yeast
and other single organism databases. Nearly 1500 links to
genes in other species now exist. Over half of these links are to 
human genes.

2. The nucleic acid sequence data libraries now attach identifier numbers
to individual coding regions within a record. This means that in a
sequence record which includes information from more than one gene, each
gene's coding region has its own identifier number (known as a PID). For
this reason nucleic acid sequence accession number cross references now
have the syntax:

accession_number; <PID_number>

e.g.: X12345; g9876543

3. The controlled vocabulary is now strictly hierarchical in organisation.

4. FlyBase now distinguishes several different classes of genetic element
and codes these in a special field (*t in star-coded output). These
include foreign and honorary genes (i.e. genes from organisms other than
drosophilids that may be used in constructs), fusion genes, transposons
(this includes all repetitive elements and sequences, regardless of
whether they are know to transpose), mitochodrial encoded genes, viruses,
pathogens and symbionts, and structural elements. See
flybase/docs/genes.doc for further information. Most of these classes are
available as individual files.

    You can use the Contact FlyBase choice on the FlyBase home page at
the URL http://morgan.harvard.edu/ to make inquiries or report problems
to flybase-help at morgan.harvard.edu, or to send updates and corrections to
the information in FlyBase to flybase-updates at morgan.harvard.edu.  



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