postdoctoral position

Akos Szakmary szakmary at
Wed Jul 30 10:35:45 EST 1997


Postdoctoral position available to study the molecular mechanisms of
DNA repair in Drosophila melanogaster. Research opportunities include
study of the in vivo functions of Drosophila Rrp1
(Recombination repair protein 1), a protein that is potentially
important in both base excision repair and recombinational repair (PNAS
88, 6780-84, 1991). Rrp1 is a homologue of the bacterial DNA repair
protein Escherichia coli exonuclease III with which it shares some
enzymatic and functional similarities. This project will focus on
developmental and genetic studies of Rrp1 function.   To date, several
transgenic lines expressing ectopic Rrp1 protein have been constructed
and used to evaluate the role of the enzyme in vivo (PNAS 93, 1607-12,
1996).  In future work, potential mutant strains will be characterized
and selected.  Strong Drosophila genetics background preferred. 
Applicants must have a Ph.D. or equivalent degree in Genetics,
Biochemistry, Molecular Biology or a closely related field. Candidates
with 0-5 years of postdoctoral experience will be considered. For more
information contact Dr. Miriam Sander (919)-541-2799.  For immediate
consideration send cover letter and CV describing research experience
to Dr. Sander in the Laboratory of Molecular Genetics, National
Institute of Environmental Health Sciences, P.O. Box 12233, Research
Triangle Park, NC 27709 (or by E-mail to sander at

NIH is an equal opportunity employer.
NIH is a Smoke-Free Environment
Smoking is not allowed in any NIEHS building

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