how much has been sequenced?

Rock Pulak rock_pulak at axyspharm.com
Mon May 1 15:01:22 EST 2000


from this page,

    http://www.fruitfly.org/sequence/

it appears that about 112 MB have been sequenced.
("As of April 29, 2000, the BDGP has sequenced:
111.4Mb total of Drosophila genomic DNA (including clones in progress)")

and, there are 1500 gaps.

and, from this page,

    http://www.fruitfly.org/sequence/faq.html#when

it appears that the estimated size of the genome is 180 MB.
("How big is the Drosophila genome? How many genes does it contain?
The genome of Drosophila melanogaster is now estimated to be 180
megabases
(Mb): the euchromatic genome is 140Mb in size, while the other
40Mb is heterochromatic (non-coding). ")

so is it correct to say that there is still 28 MB of euchromatic genomic
DNA
to sequence (and 68 MB of total genomic DNA to sequence)?
28/140 is 20%.  so 20% of the gene-rich regions hasn't been sequenced?
68/180 is about 37%.  so 37% of the total genome hasn't been sequenced?

am i in using the right numbers here?

also, does anyone know what fraction of the previously cloned genes
never showed up in the celera 12X coverage of the genome?  or how
many drosophila ESTs didn't get found in the Celera sequences?  that
might
be another way of guessing how many more genes there are out there.

thanks.

rock pulak







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