Homozygous mutant _InR_ gene lethal for D. melanogaster?

George P. Masologites guilds at mail.serve.com
Fri Sep 21 16:12:12 EST 2001


Hello,

I am reading over a report by Tatar et al in the 6 Apr 2001 issue of
Science (v. 292 pp 107-110) on the effects of mutant InR (insulin-like
receptor) genes.  It is noted that "genotypes homozygous for mutant
InR have been reported to be lethal."  At what point is it lethal?  It
is always/usually so?  Does it matter which allele of InR?

Thanks,

George
guilds at mail.serve.com




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