pna at virginia.edu
Thu Mar 28 08:43:54 EST 2002
An NIH funded postdoctoral position is available in Paul Adler's lab at the
University of Virginia to study the function of the frizzled
signaling/signal transduction pathway or the role of the tricornered kinase
in the morphogenesis of epidermal cell extensions in Drosophila. Both
pathways are known to impinge on the actin cytoskeleton, but the mechanisms
involved are not well understood. A review of these topics can be found in
Adler and Lee (2001), Current Opinion in Cell Biology 13:635-640.
Additional references for work from our lab can be found at
http://ww.minerva.acc.virginia.edu/~biology/Fac/Adler.html. Experience in
molecular biology is essential. Experience with Drosophila would be
The focus of the research will be to examine the function of additional
genes in these processes. We have identified proteins that interact
directly with Tricornered or either of two downstream members of the
frizzled pathway in the wing. Both forward and reverse genetic approaches
will be used to study the function of these candidate genes during
morphogenesis in Drosophila.
The University of Virginia is one of the leading public universities in the
United States. It is located in Charlottesville, Virginia a small but
cosmopolitan city about 2 hours south of Washington DC. Charlottesville is
routinely ranked among the best places to live in the United States.
Interested candidates should send a CV, a statement of research interests
and the names of three references to Paul Adler (pna at virginia.edu). The
position is available immediately.
More information about the Dros