GFP mouse knock-in
A. S. Goustin Lab
hivlab at CMB.BIOSCI.WAYNE.EDU
Sun Feb 1 23:49:30 EST 1998
Has anybody produced a mouse knock-in using GFP as a reporter?
In other words, has any group replaced the open reading frame of a gene
with the GFP open reading frame, so that a mouse would result in which GFP
expression would reflect the activation of that gene's regulatory
elements? Would work when the knock-in is heterozygous, so that the loss
of that gene's ORF would probably not result in a significant phenotype.
More information about the Fluorpro