marker database

David G. Kitaguchi davidk at welch.jhu.edu
Mon Aug 9 13:29:09 EST 1993


In article I7D at news.cis.umn.edu, laken at gene.med.umn.edu (Steven Laken (DGM)) writes:
~
~I am interested in a database that may be accessed for the new linkage
~analysis markers which are being produced.  Are there disks or files which
~may be downloaded?  
~
~Also, are there databases that can be directly accessed and searched.  For
~example a database that we can look at for new markers or find all
~of the different markers available on specific chromosomes.
~
~Thanks,
~
~Steve
~
~=========================================================================
~Division of Genetics and Metabolism   I
~University of Minnesota               I
~Box 485 UMHC                          I    "If all you have is a hammer,
~Harvard Street at East River Road     I     you tend to look at every
~Minneapolis, MN  55455                I     problem as a nail."
~                                      I
~Voice (612) 625-5628                  I                      -Maslow
~Fax (612) 626-7031                    I
~Email laken at gene.med.umn.edu          I
~==========================================================================
~
~
~
Hello,

For this kind of data and database please send E-mail to help at welch.jhu.edu
regarding registration.  I will trail this message with some information 
about our database.
======================================================================
 
David Kitaguchi, Sr. User System Specialist  WHOIS - DGK2
GDB/OMIM User Support                            Phone: (410) 955-9664
Johns Hopkins University School of Medicine      FAX:   (410) 614-0434 
2024 E. Monument Street
Baltimore, MD  21205-2100                          
help at welch.jhu.edu
davidk at welchgate.welch.jhu.edu

======================================================================

                          GDB(TM) and OMIM(TM)
                          ====================
 
               Gene Mapping Data and Phenotypic Descriptions
          in support of the International Human Genome Initiative

                  an international collaboration hosted at
              The Johns Hopkins University School of Medicine 
                          Baltimore, Maryland USA 

GDB (Genome Data Base)
----------------------
GDB contains human gene mapping information and has been available since
1990. Members of the Human Gene Mapping Workshops (HGMW) are responsible
for entering and continuously updating the data. Users can retrieve the
following types of information:

        o loci  (genes, fragile sites, DNA segments) arranged by map location;
                data include symbol, name, chromosome location, MIM number
        o polymorphisms and mutations
        o probes  (cloned probes, PCR primers, allele-specific nucleotides)
        o citations  (journals, books, personal communications, theses)
        o contacts  (for probes and GDB editors)
        o maps  (linkage and physical maps)
        o populations (for polymorphisms and mutations)
        o cell line definitions
        o DNA library descriptions.

There is a direct searching link through MIM numbers to the corresponding
entries in OMIM.

OMIM (Online Mendelian Inheritance in Man)
------------------------------------------
OMIM is the full-text database of Dr. Victor A. McKusick's Mendelian Inher-
itance in Man (MIM).
 
Entries are arranged by clinical disorder or trait and include the
following types of information:

        o name
        o MIM number
        o clinical observations  
        o inheritance patterns   
        o references     
        o allelic variants  (present in many entries)
        o chromosome location  (present in many entries)
        o defective gene products  (associated with many entries)
        o linkage information
        o date last edited.

Searchers can locate information in OMIM and then use the MIM number or
cytogenetic location to find additional information in GDB. 

Online Access to GDB and OMIM
-----------------------------
GDB and OMIM are available via or Internet or SprintNet(R).

   Internet access requirements:
        o communications software
           (such as the public-domain package NCSA Telnet for PC and Macintosh)

   SprintNet access requirements:
        o IBM-compatible PC, Apple Macintosh, or terminal
           (VT100 is adequate; VT220 supports function keys)
        o communications software 
           (a commercially available communications program or WelComm
           for PC / WelComm for Macintosh:  prepared specifically for
           accessing GDB/OMIM)
        o modem  (Hayes-compatible if using WelComm software)
 

Available Services
------------------
The following services are currently available at no cost.
        o account set-up
        o documentation
        o training
        o online searching
        o help-line support
        o WelComm software.

For additional information and registration, please contact:

        GDB User Support
        Genome Data Base
        Johns Hopkins University School of Medicine
        2024 E. Monument Street
        Baltimore, MD 21205 USA
        Phone:  (410) 955-7058
        Fax:    (410) 614-0434
        Internet: help at welch.jhu.edu

June 1993



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