LOD = 0.0 at all theta ???!!!

I. Fenton ifenton at crc.ac.uk
Tue Nov 16 11:39:43 EST 1993


In article <1993Nov15.162141.22091 at news.unige.ch> mike at medsun.unige.ch (Mike Morris) writes:
>  I have just run a 2 point linkage on a 60-member family, with disease
>plus 1 four-allele marker, on LINKAGE 5.2 on a Sun. The data was very
>informative, with perfect linkage.
>  MLINK with theta from 0-0.5 (inc = 0.05) gave LOD 0.0 at _all_ values!!
>  LODSCORE also gives LOD of 0.=.
>
>  Our configuration usually works, but I have not run "bigger" than about
>individuals before. Any ideas where the problem (bug?) lies?.
>
>Mike Morris PhD               * *
>Switzerland                   * *

hi mike -

why not post to the newsgroup the ped+dat-files and we can all run the
data on our versions of linkage.  also we can then laugh at the way
you have set up your liability classes...

i recnkon some cock up in the preplink-file, your fault of course.

Iain Fenton, Cardiff, UK.



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