Preplink question

Jurg Ott jo7 at COLUMBIA.EDU
Mon May 9 08:19:56 EST 1994


On Wed, 4 May 1994 pj at anat.uct.ac.za wrote:

> Could someone please explain to me why, and when, one would classify a locus
> using the binary factor option in Preplink, before using Mlink.

Binary factor notation allows representing loci with codominant and 
dominant mode (full penetrance) of inheritance while 'allele numbers' 
notation is good only for codominant loci.  Few people use binary factor 
notation, they either use allele numbers for codominant loci, or 
'affection status' notation for dominant loci (complete or incomplete 
penetrance).  The main reason why binary factor notation is used is 
probably that CEPH's database is in that notation.

Jurg Ott



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