Radiation hybrid mapping programs
fvisser at hgmp.mrc.ac.uk
Tue Dec 2 11:10:59 EST 1997
We (the UK based HGMP-RC) are thinking of providing for our users a nice
web-based interface to a radiation hybrid mapping program.
The problem with the radiation hybrid mapping programs is that there
are a number of them available, and it is not entirely clear to us
which one to provide to our users. The requirements are:
- Trusted, i.e. the algorithm/implementation is trusted by the Linkage
community to generate 'correct' results
- Batch: must be able to run without direct intervention from the user.
Most Unix based programs can do this, so that is not a big problem
- Must gave exact lod scores, not just "greater than 3" or something.
A quick perusal of the software list at rockefeller showed the
MAP+H Shields et al. PNAS 88, 6501-6505)
RHMAP (Boehnke et al, AJHG 49, 1174-1188)
RHMAPPER (Stein et al. Whitehead Institute)
I have also heard of a program called RH, and there are possibly even
more candidates. Does anyone have any suggestions which one to choose
for our interface backend?
e-mail: fvisser at hgmp.mrc.ac.uk
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